Table of contents
List of contributors
Preface to the sixth edition
1 Introduction: Two centuries of progress in transfusion medicine
Walter H. (Sunny) Dzik and Michael F. Murphy
Part I Basic Principles of Immunohaematology
2 Essential immunology for transfusion medicine
Gregory A. Denomme
3 Human blood group systems
Geoff Daniels and Sean Stowell
4 Human leukocyte antigens
Harold C. Sullivan and Caroline R. Alquist
5 Platelet and neutrophil antigens
Brian R. Curtis
6 Pretransfusion testing and the selection of red cell products for transfusion
Mark H. Yazer, Meghan Delaney and Gregory A. Denomme
Part II Complications of Transfusions
7 Investigation of acute transfusion reactions
Heather Leary, Kathryn E. Webert and Nancy M. Heddle
8 Haemolytic transfusion reactions
Edwin J. Massey, Robertson D. Davenport and Richard M. Kaufman
9 Febrile and allergic transfusion reactions
Sarah K. Harm and Mark K. Fung
10 Tranfusion-associated circulatory overload
Robert B. Klanderman and Alexander P.J. Vlaar
11 Transfusion-related acute lung injury (TRALI)
Alexander P.J. Vlaar and Rick Kapur
12 Purported adverse effects of ‘old blood’
Lirong Qu and Darrell J. Triulzi
13 Transfusion-induced immunomodulation
Neil Blumberg, Majed A. Refaai and Joanna M. Heal
14 Transfusion-associated graft-versus-host disease and microchimerism
Alexandra Budhai, Richard O. Francis and Beth H. Shaz
15 Posttransfusion purpura
Michael F. Murphy
16 Heparin-induced thrombocytopenia
Theodore E. Warkentin and Andreas Greinacher
17 Transfusion-transmitted infections
Steven J. Drews and Roger Y. Dodd
18 Bacterial contamination
Sandra Ramírez-Arcos and Mindy Goldman
19 Emerging infections and transfusion safety
Roger Y. Dodd
Part III Practice in Blood Centres and Hospitals
20 Regulatory aspects of blood transfusion
William G. Murphy, Louis M. Katz and Peter Flanagan
21 The role of hemovigilance in transfusion safety
Katharine A. Downes and Barbee I. Whitaker
22 Donors and blood collection
Marc Germain and Pierre Tiberghien
23 Blood donation testing and the safety of the blood supply
Mindy Goldman and Steven J. Drews
24 Production and storage of blood components
Marissa Li, Rebecca Cardigan, Stephen Thomas and Ralph Vassallo
25 Blood transfusion in hospitals
Zoe K. McQuilten, Erica M. Wood, Mark H. Yazer and Michael F. Murphy
26 Disaster preparedness
Heidi Doughty, Fateha Chowdhury and Richard Rackham
27 Blood transfusion in a global context
David J. Roberts, Imelda Bates, Stephen P. Field, Aggrey Dhabangi, Jean Pierre Allain and Meghan Delaney
Part IV Clinical Transfusion Practice
28 Inherited and acquired disorders of haemostasis
Irina Chibisov, Jansen Seheult and Franklin Bontempo
29 Point-of-care haemostasis testing
Katrina M. Morgan, Matthew D. Neal, Louis Alarcon and Christine M. Leeper
30 Transfusion in bleeding patients
Aaron S. Hess, Lynn G. Stansbury and John R. Hess
31 Transfusion in non-bleeding medical and surgical patients
Killian Donovan, Akshay Shah, Stuart McKechnie and Simon Stanworth
32 Transfusion in malignant haematological disease
Lise J. Estcourt and Michael F. Murphy
33 Transfusion in benign haematological disease
Eric Salazar and Christopher A. Tormey
34 Transfusion in patients with haemoglobinopathies
Yvette Tanhehco and Patricia A. Shi
35 Transfusing neonates and infants
Marianne E. Yee and Cassandra D. Josephson
36 Immunodeficiency and immunoglobulin therapy
Siraj A. Misbah
Part V Patient Blood Management
37 Development of a patient blood management programme
Jonathan H. Waters
38 Perioperative patient blood management
Martin Shao Foong Chong, Martin Rooms, Ravishankar Rao Baikady and Toby Richards
39 Restrictive transfusion practice and how to implement it
Marie A. Hollenhorst and Lawrence Tim Goodnough
40 Using data to support patient blood management
Nadia B. Hensley, Sandaruwani Abeysiri and Steven M. Frank
Part VI Cellular Therapy and Transplantation
41 Regulation and accreditation in cellular therapy
Julia Wolf, Zbigniew (Ziggy) M. Szczepiorkowski and James Griffin
42 Stem cell collection and therapeutic apheresis
Khaled El-Ghariani and Zbigniew (Ziggy) M. Szczepiorkowski
43 Haemopoietic stem cell processing and storage
Akash Gupta and Ronan Foley
44 Haematopoietic cell transplantation
Richard Salisbury, Yisu Gu, Rachael Hough and Robert D. Danby
45 CAR-T cells and recent advances in clinical cellular immunotherapy
Yisu Gu, Alex Rampotas, Connor Sweeney, David J. Roberts and Ronjon Chakraverty
46 Tissue banking
Akila Chandrasekar, Richard Lomas and Paul Rooney
Part VII Development of the Evidence Base for Transfusion
47 Observational and interventional trials in transfusion medicine
Alan T. Tinmouth, Dean Fergusson and Paul C. Hébert
48 Getting the most out of the evidence for transfusion medicine and lessons from the COVID-19 pandemic
Simon J. Stanworth, Susan J. Brunskill, Carolyn Dorée and Yulia Lin
49 A primer on biostatistics
Andrew W. Shih, Na Li, Celina Montemayor and Nancy M. Heddle
50 A primer on health economics
Seema Kacker and Aaron A.R. Tobian
51 Scanning the future of transfusion medicine
Jay E. Menitove, Paul M. Ness, Suzanne R. Thibodeaux and Edward L. Snyder
Index