Provides the most updated knowledge on the mechanisms of cancer drug
resistance and the emerging therapeutic approaches reviewed by experts
in the field
Brings detailed analyses of most important recently reported
developments related to drug resistance and their relevance to
overcoming it in cancer patients
Discusses in-depth molecular mechanisms and novel concepts of cancer resistance to conventional and advanced therapies
Table Of Contents:
1. Introductory Chapter 2. Tumor Metabolic Reprogramming in Therapeutic Resistance 3. Development of novel antiandrogens to overcome castrate resistant prostate cancer 4. Microenvironmental regulation of cancer response to therapy and therapy resistance 5. Revisiting immunogenic cell death to overcome treatment resistance in cancer immunotherapy 6. Preventing Phenotypic Plasticity in Cancer to Mitigate Therapy Resistance 7. Overcoming drug resistance in cancer with targeted radionuclide therapy 8. The PI3K pathway and chemotherapy resistance 9. Targeting leukemia stem cells in T-cell acute lymphoblastic leukemia 10. Escape from apoptosis: Anastasis as a potential mechanism of cancer drug resistance 11. From genetic data and structures to drug development: new approaches to targeting Eph receptors 12. Overcoming Therapeutic Resistance in Glioblastoma: a major clinical challenge