Patterning and Cell Type Specification in the Developing CNS and PNS, 2nd Edition - Comprehensive Developmental Neuroscience

Patterning and Cell Type Specification in the Developing CNS and PNS, 2nd Edition - Comprehensive Developmental Neuroscience


Patterning and Cell Type Specification in the Developing CNS and PNS, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, presents recent advances in genetic, molecular and cellular methods that have generated a massive increase in new information. The book provides a much-needed update to underscore the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neural patterning and cell type specification in the developing central and peripheral nervous systems.

Key Features

  • Features leading experts in various subfields as section editors and article authors
  • Contains articles that are peer reviewed to ensure accuracy, thoroughness and scholarship
  • Covers mechanisms which control regional specification, regulate proliferation of neuronal progenitors, control differentiation and survival of specific neuronal subtypes, and control the development of non-neural cells


Neuroscience, developmental biology researchers, including stem cells, aging, and diseases. Translational neuroscience researchers

Table of Contents

I: Induction and Patterning of the CNS and PNS
1. Telencephalon Patterning
S. Tole, J. Hébert
2. Morphogens, Patterning Centers, and their Mechanisms of Action
E.A. Grove, E.S. Monuki
3. Midbrain Patterning: Isthmus Organizer, Tectum Regionalization, and Polarity Formation
H. Nakamura
4. Area Patterning of the Mammalian Cortex
D.D.M. O'Leary, A.M. Stocker, A. Zembrzycki and Shenju Chou
5. The Formation and Maturation of Neuromuscular Junctions
C.R. Hayworth, R.J. Balice-Gordon
6. Neural Induction of Embryonic Stem/Induced Pluripotent Stem Cells
K. Brennand, F. Gage
7. Spinal Cord Patterning
W.D. Gifford, M. Hayashi, M. Sternfeld, J. Tsai, W.A. Alaynick, S.L. Pfaff
8. Patterning of the Diencephalon
L. Puelles, S. Martinez
9. Neural Induction Embryonic Stem Cells
C. Kintner, A. Hemmati-Brivanlou
10. Plan of the Developing Vertebrate Nervous System: Relating Embryology to the Adult Nervous System (Prosomere Model, Overview of Brain Organization)
L. Puelles
11. Cerebellar Patterning
J.K. Fahrion, Y. Komuro, N. Ohno, Y. Littner, C. Nelson, T. Kumada, B. Lamb, H. Komuro
12. Hox Genes and Neural Patterning in Drosophila
P.A. Kuert, H. Reichert
13. Induction and Patterning of Neural Crest and Ectodermal Placodes and their Derivatives
J. Begbie
14. Cerebral organoids
Jürgen Knoblich
15. Olfactory epithelium
Stavros Lomvardas
16. Patterning of reptilian forebrain
Tadashi Nomura
17. Fish patterning
Steve Wilson
18. Formation of gyri and sulci
Lisa Ronan

II: Generation of Neuronal Diversity
19. Cell Biology of Neuronal Progenitor Cells
S. Temple, Q. Shen
20. Cell Cycle Regulation in Brain Construction
M. Crespo, M.E. Ross
21. Regulation of Neuronal Survival by Neurotrophins in the Developing Peripheral Nervous System
A.M. Davies
22. Notch and Neural Development
J.J. Breunig, B.R. Nelson
23. bHLH Factors in Neurogenesis and Neuronal Subtype Specification
H.C. Lai, D.M. Meredith, J.E. Johnson
24. Environmental Cues and Signaling Pathways that Regulate Neural Precursor Development
A. Gauthier-Fisher, F.D. Miller
25. Specification of Neural Crest- and Placode-Derived Neurons
L. Sommer
26. The Specification and Generation of Neurons in the Ventral Spinal Cord
M. Matise, K. Sharma
27. Neurogenesis in the Cerebellum
V.V. Chizhikov, K.J. Millen
28. The Generation of Midbrain Dopaminergic Neurons
S.R.W. Stott, S.-L. Ang
29. Neurogenesis in the Basal Ganglia
J.L.R. Rubenstein, K. Campbell
30. Specification of Cortical Projection Neurons: Transcriptional Mechanisms
J.L. MacDonald, R.M. Fame, E. Azim, S.J. Shnider, B.J. Molyneaux, P. Arlotta, J.D. Macklis
31. The Generation of Cortical Interneurons
R. Batista-Brito, G. Fishell
32. Specification of Retinal Cell Types
R.B. Hufnagel, N.L. Brown
33. Neurogenesis in the Postnatal VZ-SVZ and the Origin of Interneuron Diversity
A. Alvarez-Buylla, F. Merkle, L. Fuentealba
34. Neurogenesis in the Damaged Mammalian Brain
M. Nakafuku, A. Grande
35. Neurogenesis in the Nematode Caenorhabditis elegans
O. Hobert
36. Development of the Drosophila Embryonic Ventral Nerve Cord: From Neuroectoderm to Unique Neurons and Glia
J. Benito-Sipos, M. Baumgardt, S. Thor
37. Neurogenesis in Zebrafish
A. Alunni, M. Coolen, I. Foucher, L. Bally-Cuif
38. Epigenetic/enhancer regulation of neural diversity
Alex Nord
39. Single cell sequencing and neuronal diversity
Alex Pollen/Tomasz Nowakowski
40. Sequential generation
Bin Chen
41. Post-transcriptional regulation of corticogenesis
Debra Silver

III: Development of Glia, Blood Vessels, Choroid Plexus, Immune Cells in the Nervous System
42. ‘Glial’ Biology: Has it Come to the Beginning of the End?
D. Rowitch, A. Alvarez-Buylla
43. Neural Stem Cells Among Glia
A. Alvarez-Buylla, A. Kriegstein
44. Structure and Function of Myelinated Axons
S.A. Buffington, M.N. Rasband
45. Mechanisms of Astrocyte Development
A.V. Molofsky, C. Hochstim, B. Deneen, D. Rowitch
46. Specification of Macroglia by Transcription Factors: Oligodendrocytes
M. Wegner
47. Specification of Macroglia by Transcription Factors: Schwann Cells
D. Meijer, J. Svaren
48. Signaling Pathways that Regulate Glial Development and Early Migration
Oligodendrocytes - R.H. Miller
49. Signaling Pathways that Regulate Glial Development and Early Migration
Schwann Cells - K.R. Jessen, R. Mirsky
50. Microglia
A.E. Cardona, R.M. Ransohoff, K. Akassoglou
51. Ependyma, Choroid
A. Meunier, K. Sawamoto, N. Spassky
52. Meninges and Vasculature
J.A. Siegenthaler, S.J. Pleasure
53. Neuron–Glial Interactions: Schwann Cells
M.H. Schwab, M.W. Sereda, K.-A. Nave
54. Neuron–Glial Interactions: Neurotransmitter Signaling to Cells of the Oligodendrocyte Lineage
L.M. De Biase, D.E. Bergles
55. Invertebrate Glia
T. Stork, M.R. Freeman
56. Nonmammalian Model Systems: Zebrafish
B. Appel
57. New Approaches in Glial Biology: Imaging Neuroglial Pathology In Vivo
I. Nikić, T. Misgeld, M. Kerschensteiner

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  • Συγγραφέας: Bin Chen
  • Εκδότης: Elsevier
  • ISBN: 9780128144053
  • Σελίδες: 1122
  • Έτος Έκδοσης: 2020
  • Διαστάσεις: 216 X 276 mm
  • Διαθεσιμότητα: Διαθέσιμο
  • 233,00€
  • 219,00€
  • Χωρίς ΦΠΑ: 206,60€

Ετικέτες: Neurology, Neuroscience