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Emerging Pathways of Vaccine Adjuvants: A Nonspecific Stimulant of the Immune System

Emerging Pathways of Vaccine Adjuvants: A Nonspecific Stimulant of the Immune System
ΝΕΟ
Emerging Pathways of Vaccine Adjuvants: A Nonspecific Stimulant of the Immune System
  • Συγγραφείς: Vivek P. Chavda, Vasso Apostolopoulos
  • ISBN: 9781394237616
  • Εκδότης: WILEY BLACKWELL
  • Σελίδες: 288
  • Διαστάσεις: 24 × 16 cm
  • Έτος Έκδοσης: 2025
295,00€
311,00€
Χωρίς ΦΠΑ: 278,30€

The book presents invaluable insights into the latest advancements, challenges, and research on vaccine adjuvants, which are key to developing more effective and safer vaccines essential for tackling pressing global health challenges.

Emerging Pathways of Vaccine Adjuvants: A Nonspecific Stimulant of the Immune System aims to drive progress in vaccine research, paving the way for the development of more potent and safer vaccines to address global health threats. This volume provides a comprehensive overview of the evolving landscape of vaccine adjuvants, encompassing a wide range of topics critical to their design, development, and application. Adjuvants play a crucial role in vaccine formulations by boosting the immunogenicity of antigens, thereby enhancing vaccine efficacy. While antigens can initiate immune responses independently, adjuvants amplify these responses. Extensive research efforts are focused on the formulation of adjuvants to establish accurate, efficient, and safe manufacturing techniques. This book provides a clear explanation of the strict regulatory issues, making it an essential resource for students, businesspeople, and academics across the globe.

Readers will find the book:

  • Encompasses current adjuvant usage and possible tactics to ensure effective production and delivery of the active constituent;
  • Presents challenges and innovations with implications to provide cheaper, more efficient solutions in the industry;
  • Prepares students for work in the industry, refining their skills for the production of critical medications.

Audience

Researchers and pharmacy students in biomedical engineering and chemical engineering, biotechnology, as well as pharmaceutical and biopharmaceutical industry engineers working in drug discovery, chemical biology, computational chemistry, medicinal chemistry, and bioinformatics.

CONTENTS

Preface xv

1 Adjuvants Boosting Vaccine Effectiveness 1
Vasso Apostolopoulos

2 In Silico Adjuvant Design and Validation for Vaccines 15
Vivek P. Chavda, Anjali P. Bedse, Pankti C. Balar, Bedanta Bhattacharjee, Shilpa S. Raut and Vasso Apostolopoulos

3 Adjuvant and Immunity 39
Himel Mondal, Shaikat Mondal, Bairong Shen and Rajeev K. Singla

4 Antigen Selection and Design 73
Pankti C. Balar, Anjali P. Bedse, Vivek P. Chavda, Chukwuebuka E. Umeyor, Prafull Kolekar, Brian O. Ogbonna, Ankita Anure, Daniel U. Eze, Payal Dodiya and Vandana B. Patravale

5 Adjuvants in Licensed Vaccines 107
Kaushika Patel, Nandita Chawla, Yashvi Mehta and Sachin Patel

6 Nanomaterial-Based Vaccine Adjuvants 137
Tanvi, Philips Kumar, Rajat Goyal, Kashish Wilson, Hitesh Chopra and Rajeev K. Singla

7 Adjuvants for Non-Invasive Routes of Vaccine Delivery 171
Shruti U. Rawal, Tosha Pandya, Mangesh Kulkarni, Riya Patel and Anjali Menon

8 Regulatory Guidelines for Vaccine Adjuvants 211
Suneetha Vuppu, Vivek P. Chavda, Toshika Mishra, Nikita Sharma and Sathvika Kamaraj

9 Adjuvant and Vaccine Safety 235
Shalini Bhattacharya, Jyoti Singh, Rupesh K. Gautam, Nadeem Farooqui, Nimita Manocha and Hitesh Malhotra

10 Shortcomings of Current Adjuvants and Future Prospects 255
Pankti C. Balar, Vasso Apostolopoulos and Vivek P. Chavda

References 260

Index 263

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Ετικέτες: vaccine , pharmacology , medicine